Table of Other Anticancer Botanicals


This list is far from comprehensive (and actually includes a couple of fungi), but it should give you a good idea of what's out there. All the compounds listed showed some kind of promise in killing cancer cells in laboratory tests. WARNING: many of the chemicals/plants listed here are deadly poisonous in even small quantities -- under no circumstances should you attempt to treat yourself or others with these compounds.

Species NameCommon Name (or Plant Type)FamilyFound inCompound (Chemical Type)
Aesculus hippocastanumHorse chestnut (tree)Hippocastanaceae
(Chestnut /Buckeye Fam.)
N. America, Europebarringtogenol-C21-angelate (terpenoid),
hippocaesculin (terpenoid)
Agrostistachys hookerin/aEuphorbiaceae
(Spurge Fam.)
India, Malaysia14-Dehydroagrostistachin (terpenoid),
agroskerin (terpenoid),
agrostistachin (terpenoid),
17- hydroxyagrostistachin (terpenoid)
Anisomeles indica (A. ovata)fang feng cao (flowering shrub)Labiatae
(Mint Fam.)
China, Indiaanisomelic acid (terpenoid),
ovatodiolide (terpenoid),
4,7-oxycycloanisomelic acid (terpenoid)
Anopterus spp.(Evergreen shrub)EscalloniaceaeTasmaniaanopterine,
hydroxyanopterine (alkaloids)
Apocynum cannabinumIndian hemp (small shrublike flowering herb)Apocynaceae
(Dogbane Fam.)
all over N. Americacymarin (glycoside)
apocymarin (glycoside)
Areca catechubetel nut (tree)Palmae
(Palm Fam.)
SE AsiaNPF- 86I polyphenols
Aristolochia tomentosawolly dutchman's pipe (climbing herbaceous flowering vine)Aristolochiaceaemuch of Eastern and Central U.S.aristolochic acid
Armoracia rusticanahorseradish (large-rooted herb)Brassicaceae
(Mustard Fam.)
Western Europe, has escaped cultivation in U.S.unknown glycoside
Asarum canadensewild ginger (creeping perennial)Aristolochiaceae
(Birthwort Fam.)
Eastern and Central U.S.aristolochic acid
Baccharis megapotamica(flowering herb)Compositae
(Sunflower Fam.)
Brazilbaccharinoids B1, B2, B3 & B7 (terpenoids)
Bolbostemma paniculatumtu bei mu (climbing vine)Cucurbitaceae
(Pumpkin Fam.)
Chinatubeimoside (terpenoid)
Brucea antidysenterica(bitter-barked tree)Simaroubaceae
(Quassia Fam.)
Africa1,11-dimethoxycanthin-6-one,
1-hydroxy-11-methoxycanthin-6-one,
bruceanols A, B & C (terpenoids),
bruceantinoside C (terpenoid),
yadanzioside N (terpenoid),
Brucea javanicaya dan zi, Kosam seed (bitter-barked tree)Simaroubaceae
(Quassia Fam.)
Chinayadanzioside O aglycone (terpenoid),
yadanzioside N (terpenoid),
yadanzioside P (terpenoid)
Bryophyllum pinnatumluo di shen gen -- "life plant" (succulent herb)Crassulaceae
(Stonecrop Fam.)
China, Taiwanbryophyllin-A (steroid)
Caltha palustriscowslip, marsh marigold (flowering marsh plant)Ranunculaceae
(Buttercup Fam.)
all over N. Americaanemonin
protoanemonin
Chelidonium majusceladine poppy (flowering herb)Papaveraceae
(Poppy Fam.)
Chinaberberine (alkaloid),
chelirubine chloride
Cicuta maculata(flowering herb)Umbelliferae
(Carrot Fam.)
N. Americacicutoxin
Cocculus trilobusfang ji (woody climbing plant)Menispermaceae
(Curare Fam.)
tropics worldwidesinococuline (alkaloid)
Combretum caffrum(tropical tree)Combretaceae
(Combretum Fam.)
S. Africacombrestatin A-1 and B-1
Cudrania cochinchinensischuan po shi (tropical tree)Moraceae
(Fig/Mulberry Fam.)
China, Hong Kongcudraisoflavone-A
Curcuma longaturmeric, jiang huang (flowering herb)Zingiberaceae
(Ginger Fam.)
worldwidecurcumin
Elephantopus carolinianuselephant's foot (flowering herb)Compositae
(Sunflower Fam.)
N. Americaisodeoxyelephantopin (terpenoid)
Elephantopus tomentosushairy elephant's foot, ku di dan (flowering herb)Compositae
(Sunflower Fam.)
China, N. Americatomenphantopin A and B (terpenoids)
Euptelea polyandraeuptelea (forest tree)Eupteleaceae
(Euptelea Fam.)
Japan3-O-acetyloleanolic acid (terpenoid)
Fagara macrophyllafagara (subtropical tree)Rutaceae
(Citrus Fam.)
Ghanadihydronitidine,
nitidine chloride
Gelsemium sempervirensAmerican gelsemium (subtropical tree)Loganiaceae
(Strychnine Fam.)
N. America12-beta-hydroxypregna-4,16- diene 3,20-dione (steroid)
Ginkgo bilobaginkgo, maidenhair tree, bai guo (subtropical tree)Ginkgoaceae
(Ginkgo Fam.)
China, Japan (cultured worldwide)bilobol,
ginkgol,
ginkgol acid
Hedychium coronariumginger lily, tu qiang huo (flowering herb)Zingiberaceae
(Ginger Fam.)
S. America, Chinacoronarins A, B, C & D (terpenoids),
Helenium autumnalesneezeweed (a daisy-like flower)Asteraceae
(Composite Fam.)
thickets and fields across N. Americahelenalin (lactone)
Heliotropium spp.heliotropes (flowering herbs)Boraginaceae
(Forget-me-not Fam.)
temperate regions worldwideindicine,
indicine-N-oxide,
lasiocarpine
Hemerocallis fulvadaylilly Liliaceae
(Lily family)
grown as an ornamental flower in many countriescolchicine
Hyptis capitaspikenard (flowering herb)Labiatae
(Mint Fam.)
Chinaursolic acid (terpenoid)
2-alpha-hydroxyursolic acid (terpenoid)
Hyptatic acid-A (terpenoid)
Inotus obliquus(wood fungus)Polyporaceaeforests worldwideinotodiol (steroid)
Ipomoea bahiensis(flowering vine)Convolvulaceae
(Morning Glory Fam.)
tropicsglycoside 1a
Iris missouriensisMissouri Iris (flowering herb)Iridaceae
(Iris Fam.)
North Americaiso-iridogermanal (terpenoid)
zeorin (terpenoid)
Juniperus virginianaEastern red cedar (evergreen tree)Cupressaceae (Cypress Fam.)Eastern and Central N. Americapodophyllotoxin
Justicia spp.(ornamental flowering herb)Acanthaceae
(Black-Eyed Susan Fam.)
S. America, Chinajusticidin A & B (aromatics)
Larrea tridentata(desert shrub)Zygophyllaceae
(Lignum Vitae Fam.)
Arizonalarreantin
Mallotus japonicus(tree)Euphorbiaceae
(Spurge Fam.)
Japanbutyrylmallotochromene,
isobutyrylmallotochromene,
mallotochromanol,
mallotolerin
Maquira calophylla(tropical tree)Moraceae
(Fig/Mulberry Fam.)
Perumaquiroside A (steroid)
Marchantia spp.(liverwort -- primitive plant) Bryophyta
(Liverwort/Moss Fam.)
forests worldwidemarchantin A
Maytenus spp.(tropical tree)Celastraceae
(Spindle Tree Fam.)
Taiwanmaytansine (alkaloid),
maytenfoliol (terpenoid)
Pancratium littorale(flowering herb)Amaryllidaceae
(Daffodil Fam.)
Hawaiilycoricidine, margetine, pancratistatin (alkaloids)
Paramichelia baillonii(tropical tree)Magnoliaceae
(Magnolia Fam.)
Thailandbisparthenolidine,
liriodenine,
oxoushinsunine (alkaloids)
Pararistolochia flos-avis(tropical vine)Aristolochiaceae
(Asarum Fam.)
Ghanaaristolactam-AII
Periploca sepiumsilk vine, xiang jia pi (climbing herb)Asclepiadaceae
(Milkweed Fam.)
Chinaperiplocoside A
Pergularia tomentosa(flowering herb)Asclepiadaceae
(Milkweed Fam.)
Saudi Arabiaghalakinoside (steroid)
Poria cocos(wood fungus)PolyporaceaeChinaMethyl deyhydrotumulosate,
methyl tumulosate (steroids)
Prunella vulgarisheal-all (low flowering perennial)Labiatae
(Mint Fam.)
native to Europe and West Asia, has escaped cult. in U.S.ursolic acid
Psorospermum febrifugum(tropical tree)Guttiferae
(Mammey Apple Fam.)
Tanzaniaacetylvismiones D & F,
deoxypsorospermin,
deoxy-4'-chlorosporospermin,
deoxysporospermin-3',4'-diol,
vismiones C & F
Psychotria forsterianaForster's psychotria (tropical shrub)Rubiaceae
(Coffee Fam.)
Vanatu, New Hebridesalkaloid B, C, D and E
Psychotria rubrared psychotria, shan da dao (tropical shrub)Rubiaceae
(Coffee Fam.)
China, Taiwanpsychorubin
Rhabdosia effusa(flowering herb)Labiatae
(Mint Fam.)
effusantin A (terpenoid)
Rhabdosia excisa(flowering herb)Labiatae
(Mint Fam.)
Chinaexcisanin A, B (terpenoid)
Rhabdosia longikaurin(flowering herb)Labiatae
(Mint Fam.)
Japanlongikaurin B (terpenoid)
Rhabdosia sculponeata(flowering herb)Labiatae
(Mint Fam.)
Chinasculponeatin C (terpenoid)
Rhabdosia umbrosa(flowering herb)Labiatae
(Mint Fam.)
Japankamebanin (terpenoid)
kamebakaurin (terpenoid)
leukamenins A & B (terpenoid)
umbrosin A (terpenoid)
Ricinus communiscastor oil, bi ma zi (flowering herb)Euphorbiaceae
(Spurge Fam.)
N. America, Europe, Chinaricin A
Sanguinaria canadensisbloodroot (flowering herb)Papaveraceae
(Poppy Fam.)
woodlands throughout the Eastern and Central U.S.sanguinarine (alkaloid)
Schisandra propinqua(woody climbing plant)Schisandraceae
(Schisandra Fam.)
China & SE Asiamanwuweizic acid (steroid)
Simaba multiflora(bitter barked tree)Simaroubaceae
(Quassia Fam.)
French Guiana13,18-dehydro-6-alpha senecioyloxychaparrin (terpenoid)
Solanum dulcamarabittersweet woody nightshade (woody climbing vine)Solanaceae
(Nightshade Fam.)
Europe and N. Americaunknown alkaloid
Spathelia sorbifolia(tropical shrub)Rutaceae
(Citrus Fam.)
Jamaicamethylsorbifolin,
spatheliachromen
Stizophyllum riparium(twining tree)Bignoniaceae
(Catalpa Fam.)
Perustizophyllin (steroid)
Strebulus asper(tropical shrub)Moraceae
(Fig/Mulberry Fam.)
Thailandmansonin (steroid),
strebloside (steroid)
Strychnos usambarensis(tropical shrub)Loganiaceae
(Strychnine Fam.)
Central Africaakagerine,
dihydrousambarensine,
hydroxyusambarine,
strychnopentamine,
strychnophylline,
usambarine,
usambarensine (alkaloids)
Taxus maireiyew (Evergreen shrub)Taxaceae
(Yew Fam.)
Chinataxamairins A & B (terpenoids),
Thalictrum sessilemeadow-rue (flowering herb)Ranunculaceae
(Buttercup Fam.)
China, Taiwanberberine, liriodenine, oxoushinsunine, thalicarpine (alkaloids)
Tripterygium regeliiyellow vine (subtropical climbing plant)Celastraceae
(Spindle Tree Fam.)
Chinaregelin (terpenoid),
regelinol (terpenoid),
triptolide (alkaloid)
Vismia spp.(tropical tree)Guttiferae
(Mammey Apple Fam.)
Venezuelaacetylvismione B,
desacetylvismione A,
vismione A & B,
Wikstroemia elliptica(tropical shrub)Thymelaeaceae
(Daphne Fam.)
Hawaiidaphnoretin (flavan),
lariciresinol (aromatic),
methoxylariciresinol (aromatic),
syringaresinol (aromatic),
umbelliferone (quinone)
Wisteria brachybotryswisteria (viney herb)Leguminosae
(Acacia/Pea Fam.)
Japanafromosin (flavan)
Yucca glaucasoapweed yucca (blue-green perennial w/ stiff, swordlike leaves)Liliaceae
(Lily Fam.)
Western U.S. and Mexicowater extracts have antitumor activity against B16 melanoma in mice

References:

Duke, James A., and Edward S. Ayensu. 1985. Medicinal Plants of China. Algonac, MI, Reference Publications, Inc.

Duke, James A., and Steven Foster. 1990. A Field Guide to Medicinal Plants of Eastern and Central North America. New York, NY, Houghton Mifflin Co.

Heywood, V.H., ed. 1993. Flowering Plants of the World. New York, NY, Oxford University Press.

Pettit, George R., Fiona Hogan Pierson, and Cherry L. Herald. 1994. Anticancer Drugs From Animals, Plants and Microorganisms. New York, NY, John Wiley & Sons, Inc.


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